What is Synapse?
Synapse is the latest platform to combine drug discovery and development sources with best-in-class AI technology to provide insight into early R&D innovation. The searching capabilities combined with knowledge graphs and dashboards allow innovators to study relationships between entities and gain competitor insights.
With Synapse, PatSnap hopes to support innovators in their research phase and shorten the time it takes for the drug to go from ideation to market approved.
Within Synapse data can be organized in one of two ways: Dashboards or Knowledge Graphs. Both data organization types are interactive and allow the user to delve deeper into their area of research
Data Coverage in Synapse
Synapse pulls data related to drugs, diseases, targets, and organizations. The results are organized by news articles, non-patent literature patents, and clinical trials. Depending on the result set being viewed, different can be used to sort find the most relevant data. Users can use dashboards to keep track of their company, drug, or target of interest.
What is a Knowledge Graph?
The Knowledge Graph in Synapse is used to show relationships between drugs, targets, diseases, organizations and additional data. Analyzing these relationships can build a road map of what future research may be done on a drug or target. For example, we can look at a Drug Repurposing Workflow.
How to use Knowledge Graphs?
- Click “Enter KG” from the results page.
- A new tab will appear, in which your drug or target of interest will be listed inside a colored circle.
- Double-clicking on the drug/target of interest will open a 4-coloured ring around the subject of interest. Each quadrant of these rings will list the familial Hierarchy, Diseases, Targets, and Organizations related to the searched subject.
- Clicking on quadrants of interest will allow the user to map out the relationships of interest from the search subject to the related results.
- To study the direct relationship between multiple entities, hold the “Shift” key down on your keyboard and select the different nodes of interest.
- A pop-up will appear displaying the number of common documents between the selected nodes. Tip: The selected nodes will be highlighted in yellow.
- The ‘Find Relationships’ button on the top right-hand corner of the screen will be activated. You can then use the options listed to view the filtered relationships between the selected entities. To further refine the results of the Knowledge Graph generated at this point use the gear icon in the top right corner to filter results. Tip: This opens a new Knowledge Graph.
- Once the Knowledge Graph has been filtered to your liking use the highlighter icon to view the relationships between the entities in the Knowledge Graph. Tip: Selecting a relationship will highlight the connecting lines between entities.