Search by antigen. Explore validated antibody pairings. Accelerate therapeutic discovery.

What is the Antibody R&D module?

The Antibody R&D module is a newly launched feature in PatSnap Bio designed specifically for users in discovery biology, translational medicine, and therapeutic R&D. Unlike Bio’s existing patent-centric tools, this module pivots from sequence-only data toward functional antibody-antigen relationships, helping researchers answer one critical question:

“Given an antigen of interest, what validated antibodies bind to it?”

This opens up powerful new workflows for target validation, antibody discovery, optimization, and repurposing.

Use Case?

Traditional sequence search is optimized for IP use cases—FTO analysis, novelty checks, claim matching. But modern R&D teams need more. Specifically:

• Pairing data between antibodies and their targets

• Insights on binding strength, epitope location, and sequence relationships

• Large, well-curated datasets that can be used for machine learning models or manual hypothesis generation

• The Antibody R&D module addresses these unmet needs, offering a focused entry point into high-quality Ab–Ag data.

Paired Antibody–Antigen Data

• 200K antibody sequences

• 185,000+ Ab–Ag pairings

• Covering ~4,400 targets, 3.1K+ with Uniprot IDs

• 22K+ affinity, 24K+ IC50/EC50

• 89% of data is patent-derived, with the remainder from NCBI, PDB, and drug annotations

• Mostly monoclonal antibodies, with some Fab, ScFv, and bispecific formats

• Sequences are unprocessed and mapped to Swiss-Prot reviewed Uniprot IDs wherever possible

• Complex targets (e.g. protein families or pathogens) may not have a Uniprot ID, but are still included by name

Each pairing is grounded in primary source material, ensuring relevance for both exploratory and production use cases.