Below is a description of the most commonly used advanced preferences available on the PatSnap Bio platform
Sequence Identity- This allows you to set what percentage match is allowed in your results. This includes the characters used in the sequence and alignment. The higher the percentage the closer the results should match your sequence.
Query Coverage- This specifies the percentage of your query sequence you wish to match. For example if I search for a sequence that contains 100 amino acids and I would like to see sequences that match at least 70 amino acids of my query sequence then I would change the slider to 70% to 100%. This will not take account into positioning of the amino acids.
Match with Gaps- Allows for sequences to match and found in your results if the result sequences displays a gap rather than an amino acid.
E-Value - indicates how likely it is that a sequence is similar to yours simply by chance. For instance, if your sequence is very short, there is a higher likelihood that it appears in several locations simply by chance. The greater the e-value, the more likely it is that this is just down to luck.
Algorithm- There are 3 algorithm to choose depending on the search you wish to perform.