Combined Search

Learn how to use the Combined Search in Patsnap Bio to search up to six sequences simultaneously and identify patents or literature containing multiple sequences of interest. This video covers configuring queries, interpreting the common patent heatmap, and filtering, saving, or exporting relevant results.

• In Patsnap BIO, go to the Scenario section on the left-hand side.
  
  Select Combined to open the Combined Search workflow.
  
  This search mode is designed to help you find patents or literature documents that mention more than one sequence of interest.
• Combined Search lets you run up to six sequence queries at the same time.
  
  Click Add Another Sequence to add more query fields until you reach six.
  
  Each query can be configured independently, so you can set different advanced preferences for each one.
  
  You can also mix sequence types in the same search:
  
  Example: Query 1 can be an amino acid sequence.
  
  Example: Query 4 can be a nucleotide sequence.
• Use Combined Search to search across the patent landscape.
  
  You can also use it to search within literature documents.
  
  After entering your sequences and settings, click Search.
  
  If you searched literature as well, a separate tab will be available for those results.
• The first chart in the top-left shows the individual results for each query.
  
  This view displays the pure sequence matches and associated patent results for each sequence separately.
  
  At this stage, you are not yet viewing combinations of sequences.
• Scroll down to the Common Patent Heat Map to see where multiple sequences appear together in the same patent.
  
  The heat map gives a visual summary of which sequences were identified within each patent.
  
  Use the heat map to quickly spot documents with overlapping sequence hits.
• The numbers in the heat map show how many sequences matched in each patent.
  
  The color scale shows the alignment identity of the identified sequences.
  
  Refer to the legend to understand what each color means.
• Use the detailed breakdown below the heat map to inspect the sequence matches more closely.
  
  Apply the filters on the left-hand side to narrow the results.
  
  A particularly useful option is the In Claims filter:
  
  Helpful for freedom to operate analysis.
  
  Use it when you only want patents where the hit sequences appear in the claims.
• Open the Settings section if you want to change how results are displayed.
  
  You can adjust:
  
  Grouping preferences
  
  Translation settings
  
  Use these options to better organize the results for your analysis.
• Once you have filtered down to your final set of results, you can:
  
  Export the results
  
  Save them to a workspace
  
  View in Analytics for additional IP-focused filtering
  
  This helps you prioritize the most relevant documents for your analysis.